With so many genetic organisms to choose from, it can be difficult to find the organism that fits your instructional and time needs. Do you need a specimen that requires no culturing and is ready to use out of the box like genetic corn ears for mono and dihybrid traits? Do you want students to perform their own genetic crosses and grow multiple generations as with Wisconsin Fast Plants® or Drosophila?
No matter the curricular need or available classroom time, Carolina has you covered. This guide offers benefits, best uses, time requirements, and example lessons for each of our most popular genetic organisms, making it easy to find the best fit for you and your students.
Grade level: Middle school, high school, and college
Best use(s): Monohybrid and Dihybrid traits; Chi-square statistical analysis
Benefits: Reusable and ready to use out of the box
Genetic corn ears feature kernels that demonstrate traits that are easy to identify and score, and that align with traditional Mendelian ratios. Our monohybrid and dihybrid genetic corn show the inheritance patterns for kernels that are purple (R), yellow (r), starchy/smooth (Su), and sweet/wrinkled (su)—just as predicted with Mendel’s laws.
Activities using genetic corn often involve students making predictions using Punnett squares and comparing their predicted phenotypic ratios to the ratios found on actual genetic corn ears by counting their kernels. Chi-square analysis can be conducted to further determine if Mendel’s predicted ratios are supported or rejected by the actual phenotypic ear kernel count.
The lesson “Corn as an Introduction to Mendelian Genetics” is one of the many activities that can be performed using genetic corn.
As an introductory activity for middle school or early high school, the Monohybrid Genetics with Corn Kit covers the basics of Mendelian genetics, including the inheritance of a single pair of alleles, one of which is dominant and the other recessive. Students score the phenotypes of the F2 and compare their data to their predictions.
Designed for advanced high school or introductory college-level classes, this comprehensive kit covers all the basics of Mendelian genetics such as segregation, independent assortment, and monohybrid and dihybrid crosses, while also providing opportunities for analyzing data using Chi-square analysis.
Purple Starchy:Purple Sweet:Yellow Starchy:Yellow Sweet. The result of testcrossing the F1 hybrid with the recessive parent (R/r Su/su x r/r su/su).
Starchy:Sweet. An F2 ear from a cross between a starchy (Su/Su) and a sweet (su/su) parent. The sweet seed are wrinkled and the starchy seed are smooth.
Purple:Yellow. The result of testcrossing the F1 hybrid with the recessive parent (R/r × r/r).
Grade level: Middle school, high school, and college
Best use(s): Monohybrid traits; albinism; Chi-square statistical analysis
Benefits: Results in only 14 days
Genetic corn seeds will grow into seedlings with identifiable phenotypes for genetic studies in as little as 14 days. Simply plant, water, and watch an excellent demonstration of germination as seedlings appear with traits consistent with Mendelian ratios.
Genetic corn seeds are available with monohybrid traits, such as tall (D) and dwarf (d) or green (G) and albino (g), or as a dihybrid F2 seed demonstrating tall green:tall albino:dwarf green:dwarf albino (9:3:3:1). In addition to scoring of genetic ratios, corn seeds can provide a great example of albinism and its viability.
Activities with genetic corn often involve students counting the phenotype of corn seedlings to identify predicted Mendelian ratios with the potential addition of Chi-square analysis. Unique to the green:albino corn seed, an investigation into population genetics and lethal traits, such as albinism, can also be conducted for greater depth into genetics studies.
The perfect budget-friendly tool for teaching Mendelian genetics—your students witness dominance/recessiveness firsthand! Seedlings segregate in a ratio of 3 green:1 albino, and students can infer that the parent plant was heterozygous for albinism.
About 100 F2 seeds give a ratio of 3 tall:1 dwarf in the seedlings, making this a great tool for demonstrating monohybrid Mendelian genetics.
To facilitate the use and understanding of biotechnology applications in the environment, students clone promoters into the plasmids, pClone Red and pClone Blue, using the technique of Golden Gate Assembly (GGA). Then students are tasked with performing a transformation on E. coli cells to produce new ampicillin-resistant colonies expressing their designed plasmids. #211150
Students discover CRISPR technology while understanding basic concepts and historical development of biotechnology with this truly unique, hands-on CRISPR gene-editing kit. As your students explore Nobel Prize-winning technology, they walk in the footsteps of science pioneers and use the same techniques that scientists across the world have used to solve the global problems of tomorrow. #216900
To facilitate the use and understanding of biotechnology applications, students complete procedures for preparing 3 agarose gels and separating samples of bromophenol blue, albumin, and hemoglobin. #211385
Our simplest PCR kit is designed to offer unmatched versatility. This approachable protocol has been optimized for the classroom, and it works flawlessly with or without access to a thermal cycler. #211222
Analyze the fundamental components of biotechnology, by using β-thalassemia as a medical example, as students explore the phenomenon of gene regulation. They investigate why changes in the DNA sequence in front of a gene affect how much functional protein is produced by the gene. #211100
To facilitate the use and understanding of biotechnology applications, students complete procedures for preparing 3 agarose gels and separating samples of bromophenol blue, albumin, and hemoglobin. #689800
Analyze the fundamental components of biotechnology as students conduct experiments and analyze data over the course of this 5-day lab to understand the relationship between a phage called Andhra and its staphylococcus host. Their goal is to answer the driving question: How can we use evidence to model phage-host interactions and therefore explain the impact of a CRISPR-Cas system on bacterial survival? #211772
Analyze the fundamental components of biotechnology as students perform a foundational experiment to demonstrate cell communication in yeast reproduction. They study the yeast life cycle to determine if and how cells communicate by observing yeast morphology. They design an experiment using different mating types of yeasts, culturing techniques, and microscopy to provide evidence that single-celled organisms communicate. #173610
Understand basic concepts and historical development of biotechnology. RNA interference (RNAi) is a technique that allows you to silence the expression of a chosen gene by specifically degrading the gene’s mRNA, making use of a Nobel Prize-winning technique to silence the dpy13 gene in the nonparasitic roundworm C. elegans. #211392
Analyze methods for protecting the safety of biotech workers and the public by exploring infectious diseases using a hands-on simulated ELISA assay, a common laboratory technique used to test blood serum for antibodies against disease-causing agents including HIV, Lyme disease, avian influenza (bird flu), or West Nile virus with 1 simulated antigen. #211248
Understand the science of plants in agricultural biotechnology by extracting DNA from wheat germ. Wheat germ is ground, the cells are lysed, and cellular contents are released. Extracellular protein is digested by enzyme treatment and heating, then spooled on a stirring rod. #154704
Understand the use of biotechnology applications in the environment by exploring the evolution of fish species through protein analysis. Students perform gel electrophoresis on extracted muscle protein mixtures from 7 different types of fish, creating a unique protein fingerprint for each fish species, then hypothesize the degree of relatedness of the fish and compare their ideas to a standard evolutionary tree of fish. #211255
Understand the use of biotechnology applications in the environment in the growing field of eDNA by challenging them to participate in ongoing research to monitor the prevalence of antibiotic-resistant bacteria in soil. Students collect soil samples, extract environmental DNA from soil, and use PCR and gel electrophoresis to test their samples for evidence of tetracycline resistance. #211395
Students gain hands-on, career-ready experience in the biology and chemistry of cheesemaking. They learn about the connection between enzymes, pH, and microbes and study their role in the cheesemaking process. Kit supplies enough materials for 30 students working in pairs and includes free, 1-year access to digital resources. #202306
Tall Green:Tall Albino:Dwarf Green:Dwarf Albino (9:3:3:1). F2 seed showing the segregation of 2 independent plant characteristics, dwarf (d5) and albino (lw3). About 100 seed.
Early monocot development from seed to young plant with secondary roots and leaves. Includes an instructional illustration. Size, 3-1/2 x 3-1/2".
1:1. F2 seed giving a ratio of 1 tall:1 dwarf in the seedlings. About 100 seed.
Grade level: Elementary, middle school, high school, and college
Best use(s): Monohybrid and dihybrid traits; plant biology and multigenerational studies
Benefits: Diverse selection of phenotypes; 40-day life cycle; students perform the genetic cross, growing F1 and F2 seeds simultaneously; easy to care for; excellent source of large data sets
Wisconsin Fast Plants® feature many easy-to-identify phenotypes with a diverse range of different stem colors, leaf shapes, hairiness, height, and more. In as little as 15 days, planted Fast Plants® will reach maturity, demonstrate target phenotypes, and produce flowers ready to be pollinated for producing the next generation of your study. This provides not only rapid genetic data but also an opportunity for students to experience a complete plant life cycle and engage in plant breeding.
To use Fast Plants®, a variety of growing methods and learning objectives are available to choose from. Teachers seeking the quickest and easiest way to demonstrate Mendelian ratios often select our Wisconsin Fast Plants® 72-Hour genetics kits, which feature observable phenotypes to score in only 72 hours, or our Wisconsin Fast Plants® seed disks, which have seeds stitched into a disk for easy planting and plant separation.
For a complete and in-depth genetics study using Fast Plants®, growing systems or deli containers can be used with proper lighting to grow any of the large number of seed varieties available to meet a teacher’s objective in covering monohybrid traits, dihybrid traits, selection, and other subjects. For an example of a Fast Plants® lesson, please visit the Carolina Knowledge Center.
Students germinate seeds from P1, P2, F1, and F2 generations. They observe the seedlings from P1 and F1 and construct an inheritance pattern model to predict the phenotype and genotype of P2 and what the F2 seedlings will look like. After they examine the actual P2 and F2 seedlings, they can revise their model and explain the results based on the data they collected. The driving question that students investigate is, “How do trait variations in Fast Plants® seedlings reveal inheritance patterns?”
For a class of 32 students. How are traits passed from one generation to the next? In this 60-day investigation, students observe 3 generations of plants as they attempt to unravel the mystery of paternity. As the activity progresses, students develop explanations based on their own observations for the inheritance of 2 Mendelian genes. Kit includes everything needed except water and a light source.
1:1. F2 seed giving a ratio of 1 tall:1 dwarf in the seedlings. About 100 seed.
Grade level: High school and college
Best use(s): Monohybrid and dihybrid traits; sex-linked traits and gene linkage
Benefits: Large variety of phenotypes; students perform the genetic cross themselves; ideal for advanced topics in genetics or studies that require large data sets
Drosophila is one of the most widely used model organisms. With an incredible diversity of traits to study and a 2-week life cycle, genetic studies with Drosophila enable students to experience authentic genetic crosses over multiple generations in a relatively short time.
While Drosophila offers excellent and easy-to-identify examples of monohybrid and dihybrid traits with mutations such as reduced wings (apterous) and ruby-red eyes (sepia), it is the ability to study sex-linked traits and gene linkage that are conceptually unique to Drosophila compared to our other genetic organisms.
Working with Drosophila may appear intimidating at first, but Carolina has spent decades developing products and support to provide you with confidence when using Drosophila in your classroom. Drosophila experiments begin by either selecting 2 parent strains to cross from our over 40 unique strains or by obtaining pre-crossed F1 cultures. Our cultures arrive to you with food included and will mature into adults ready for examination.
To analyze your Drosophila, simply add FlyNap Anesthetic to a wand and insert it into a culture to safely anesthetize flies for examination. Under a dissecting scope, students can then easily score traits to observe firsthand the genetic ratios resulting from their crosses. Explore example lessons and instructional videos below to preview how easy and insightful it can be working with Drosophila.
Students study monohybrid genetics using flightless fruit flies. They cross miniature apterous (wingless) with miniature (serves as wild type) to investigate the inheritance of wings. The F1 have wings, while the F2 show a 3:1 ratio of winged to apterous.
This engaging hydroponics setup is sure to interest and excite your students as they observe complete plant development by growing herb plants from seed. The kit allows students to observe the aspects of plant development without the use of soil. #159610 Experiments with Drosophila just got easier. Each Easy Fly® culture is heat shocked prior to shipping to kill all the males. Adults and pupae in an Easy Fly® culture are all females. In this kit, students study dihybrid inheritance by crossing apterous (wingless) males with sepia (brown eye color) Easy Fly® females. Materials are sufficient for a class of 32 students working in groups of 4.
The Drosophila Sex-Linked Cross Kit demonstrates sex-linked inheritance using white-eyed and red-eyed (wild type) Drosophila. Kit includes a voucher to request the perishable materials later at your convenience. Contact Carolina or return the voucher to request delivery of perishables.
A complete guide for maintaining and studying Drosophila. Our manual features detailed explanations and sound suggestions for virtually every aspect of using fruit flies for studying genetics.
Never buy or use separate anesthetizer chambers again! With the FlyNap® Anesthetic Kit you can anesthetize Drosophila in their own culture vessels, eliminating the need to transfer Drosophila and decreasing the risk for dosage error.
Grade level: High school and college
Best use(s): Meiosis; crossing over; gene mapping
Benefits: Easy to grow and visualize; works as demonstration or for lab activities.
Fungi are very diverse and easy to work with, with morphology that offers an amazing opportunity for students to see crossing over and recombination firsthand. One species, Sordaria fimicola, forms filaments that are transparent, enabling students to view dark or light embryos, whose order demonstrates if crossing over has occurred. Four dark or light alternating embryos in a row indicates no crossing over, and any other combination indicates that crossing over has occurred. This powerful observation allows students to calculate gene maps and rates of recombination.
Sordaria fimicola is studied in a variety of ways. As a demonstration of crossing over, already crossed plate cultures or prepared slides are often used for microscopic examination to count rates of crossing over. For a more robust investigation, strains of wild type, mutant gray, and mutant tan can be obtained for students to perform crosses between the wild type and each respective mutant. The results are then counted and analyzed for recombination rates and gene mapping. However sophisticated your genetic studies need to be, Sordaria fimicola offer versatility and are much easier to maintain than other living cultures.
Students cross the wild-type Sordaria strain with the mutant tan strain. Hybrid asci are produced containing 4 dark-colored and 4 light-colored ascospores. Students then use tetrad analysis to calculate the gene-to-centromere distance in map units for the mutant tan gene.
A cross of Sordaria fimicola wild type and the mutant tan strain for demonstrating genetic crossing-over. For use with Advanced Placement® Biology Laboratory #3 or as a separate refresher demonstration from the exercises found in our Sordaria genetics kits. AP® is a trademark registered and/or owned by the College Board®, which was not involved in the production of, and does not endorse, these products.
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