GENBIO TOPIC

Cell Structure and Function

Cells are the building blocks of all organisms.

GENBIO TOPIC

Cell Structure and Function

Cells are the building blocks of all organisms.

High School (NGSS-aligned) Learning Goals

1

Identify Organelles

Identify organelles and describe functions.

2

Compare Cells

Compare plant and animal cells.

3

Distinguish Cell Types

Distinguish prokaryotic and eukaryotic cells.

4

Use a Microscope

Observe cells using a microscope.

5

Explain Life Processes

Explain how cell structures support life processes.

1. Identify Organelles

Identify organelles and describe functions.

2. Compare Cells

Compare plant and animal cells.

3. Distinguish Cell Types

Distinguish prokaryotic and eukaryotic cells.

4. Use a Microscope

Observe cells using a microscope.

5. Explain Life Processes

Explain how cell structures support life processes.

College Intro Biology Learning Goals

1

Predict Structure–Function Change

Predict how changes in organelle structure affect cell function.

2

Analyze Cell Types

Analyze similarities and differences among major cell types.

3

Relate to Evolution

Relate cell organization to evolution and phylogeny.

4

Interpret Microscopy Data

Collect, analyze, and interpret microscopy data.

5

Connect to Homeostasis

Connect organelle function to cellular pathways and homeostasis.

1. Predict Structure–Function Change

Predict how changes in organelle structure affect cell function.

2. Analyze Cell Types

Analyze similarities and differences among major cell types.

3. Relate to Evolution

Relate cell organization to evolution and phylogeny.

4. Interpret Microscopy Data

Collect, analyze, and interpret microscopy data.

5. Connect to Homeostasis

Connect organelle function to cellular pathways and homeostasis.

Cell Structure & Function Core Concepts

Cells are the building blocks of all organisms. The organelles and characteristics of a cell determine its role within the organism. Understanding the relationship between a cell’s structure and function is a foundational concept in biology, helping students connect molecular processes to the systems and organisms they study.

Understanding cell structure and function is essential for topics such as biochemistry, genetics, microbiology, anatomy and physiology, pathology, and more. As students explore cell biology through observation, investigation, and experimentation, they develop critical laboratory skills including microscopy, data collection, visual documentation, analysis, scientific communication, and problem solving. These transferable skills support success across STEM disciplines and help students make real-world connections to scientific and healthcare careers.

This guide breaks down the important information students need to know, provides links to products and free digital resources, and includes suggestions for hands-on labs that reinforce student understanding and support learning outcomes.

We’ve gathered a variety of products and resources to better help you teach this concept. They include:

Key Topics Covered

Cell Theory

Modern cell theory rests on a few core principles:

  1. All living things are made of cells — organisms can be unicellular or multicellular.
  2. The cell is the smallest unit capable of carrying out life’s processes.
  3. Every cell arises from a pre-existing cell.
  4. Genetic information passes from parent cells to daughter cells.*
  5. Cells carry out metabolic processes and maintain homeostasis.*
  6. Cells share similar chemical components.*


*Suited for advanced courses such as AP and college-level biology.

Prokaryotic vs. Eukaryotic Cells

Cells fall into one of two broad categories, prokaryotic and eukaryotic. Bacteria and Archaea are classified as prokaryotic (pro- meaning before and -kary meaning nucleus, so “before nucleus”). Plants, animals, and fungi are eukaryotic (eu- meaning true, so “true nucleus”). Most prokaryotes are very small, and all lack membrane-bound organelles. They contain DNA, a cell membrane, and ribosomes. Eukaryotes have many membrane-bound organelles that serve specialized purposes.

Observing single-celled organisms is a great way to introduce cells in your lab. Although prokaryotic cells lack a nucleus and membrane-bound organelles, they allow students to learn about basic cell morphology, reproduction, and evolution. Introduce eukaryotic cells to students with protists. Students can observe nuclei, organelles, and movement under the microscope!

Organelles and Their Functions

In eukaryotic cells, there are many specialized structures called organelles that carry out specific functions like metabolism (mitochondria and chloroplasts), protein synthesis and transport (ribosomes and endoplasmic reticulum), storage and transport (vesicles and vacuoles), and waste management (peroxisomes and lysosomes).

Plant Cells vs. Animal Cells vs. Fungi Cells

Plants, animals, and fungi all have important structural differences that both arise from and determine their role in the environment and reflect how each organism lives, grows, and obtains energy. Plants and fungi rely on their cell walls for structural support, while animals developed specialized tissues and organs for that purpose. By exploring the similarities and differences between the cells of different organisms, students can better understand how cellular adaptations support the survival of different organisms.

Structure-Function Relationships

Each organelle is specialized to perform specific tasks within the cell, and their structure reflects that. For example, the large membrane areas of the chloroplast and mitochondria allow for a greater number of membrane-mediated reaction sites. By examining the relationship between cellular structures and their functions, students can better understand how cells operate as integrated systems and how specialized organelles enable organisms to grow, respond to their environment, and survive.

Prokaryotic vs. Eukaryotic Cells

Cells fall into one of two broad categories, prokaryotic and eukaryotic. Bacteria and Archaea are classified as prokaryotic (pro- meaning before and -kary meaning nucleus, so “before nucleus”). Plants, animals, and fungi are eukaryotic (eu- meaning true, so “true nucleus”). Most prokaryotes are very small, and all lack membrane-bound organelles. They contain DNA, a cell membrane, and ribosomes. Eukaryotes have many membrane-bound organelles that serve specialized purposes.

Observing single-celled organisms is a great way to introduce cells in your lab. Although prokaryotic cells lack a nucleus and membrane-bound organelles, they allow students to learn about basic cell morphology, reproduction, and evolution. Introduce eukaryotic cells to students with protists. Students can observe nuclei, organelles, and movement under the microscope!

Organelles and Their Functions

In eukaryotic cells, there are many specialized structures called organelles that carry out specific functions like metabolism (mitochondria and chloroplasts), protein synthesis and transport (ribosomes and endoplasmic reticulum), storage and transport (vesicles and vacuoles), and waste management (peroxisomes and lysosomes).

Plant Cells vs. Animal Cells vs. Fungi Cells

Plants, animals, and fungi all have important structural differences that both arise from and determine their role in the environment and reflect how each organism lives, grows, and obtains energy. Plants and fungi rely on their cell walls for structural support, while animals developed specialized tissues and organs for that purpose. By exploring the similarities and differences between the cells of different organisms, students can better understand how cellular adaptations support the survival of different organisms.

Structure-Function Relationships

Each organelle is specialized to perform specific tasks within the cell, and their structure reflects that. For example, the large membrane areas of the chloroplast and mitochondria allow for a greater number of membrane-mediated reaction sites. By examining the relationship between cellular structures and their functions, students can better understand how cells operate as integrated systems and how specialized organelles enable organisms to grow, respond to their environment, and survive.

Hands on Activities

Build deeper understanding and comprehension of cell structure and function with hands-on activities that place key concepts at students’ fingertips.

Best for First Introduction

These activities introduce students to foundations in cell structure and function, building a base for future concepts.

Discovering Bacteria Types Self-Study Unit, Microscope Slide Set

Discovering Bacteria Types

Microscope slide shows 3 typical bacterial forms in separate smears. Unit includes a self-study card and labeled photograph with descriptive text.

Discovering Plant Cells

Discovering Plant Cells

The Discovering Plant Cells Set includes slides of the 2 most commonly studied examples of plant cells (onion bulb epidermis and privet leaf).

Origami Organelles™ 3-D Paper Model Kit: Plant Cell

Origami Organelles™ 3-D Paper Model Kit: Plant Cell

Models are powerful tools for teaching science as they provide useful simplifications of structures and processes, helping to make the unseen seen and the complex simple. Your students will enjoy learning about plant cells with this colorful model. It covers all the main parts of the plant cell, including the cell membrane, cell wall, chloroplasts, nucleus, chromosomes, and mitochondria. For more advanced learners, you can extend the model with the included optional organelles to study rough ER, smooth ER, and Golgi apparatus.

3-D Paper Model Kit: Animal Cell

3-D Paper Model Kit: Animal Cell

Use this easy-to-assemble model to teach students about the animal cell. This colorful model and accompanying information cover cell parts, including the cell membrane, nucleus, chromosomes, and mitochondria. For more advanced learners, optional extensions include rough endoplasmic reticulum, smooth endoplasmic reticulum, and Golgi apparatus.

Best for Advanced Students

These advanced activities help students build on foundations covered in earlier lessons and develop advanced microscopy skills.

Inquiries in Science®: Investigating Cell Types

Inquiries in Science®: Investigating Cell Types

Students explore the cell as the basic unit of life. Using a guided-inquiry technique, they first view cells with a microscope (not included). They then study Euglena, Paramecium, and elodea samples and observe their responses to different environmental conditions. As a final assessment, students design their own experiment to test cellular responses to environmental changes of their choice.

Protozoa Survey Set

Protozoa Survey Set

Set consists of 6 individually labeled cultures: Amoeba, Euglena, Paramecium, Stentor, Volvox, Spirostomum. Use this Lab Sheet to guide you through the activity.
Typical Animal and Plant Cells Slide Kit

Typical Animal and Plant Cells Slide Kit

This kit demonstrates the typical similarities and differences between animal and plant cells. Students prepare slides of their own cheek cells and an onion bulb epidermis. 

Elodea

Elodea

In this lab, students observe Elodea leaves under magnification. They will see cell walls and chloroplasts. From the movement of chloroplasts they will infer that cyclosis, or protoplasmic streaming, is occurring. They also will observe that most chloroplasts are pressed tightly against the cell wall and should infer from this that much of the cell is occupied by a vacuole.

Best for Hands-on Investigation

Students explore topics like cell structure and function of animal cells, plant cells, and protists with these hands-on activities.

DNALC Baggie Cell Model Kit

DNALC Baggie Cell Model Kit

Introduce students to the concept of “form fits function” by familiarizing them with different kinds of cells, their organelles, and the specific jobs each organelle performs. Students work in pairs to build a model animal cell using common materials. Each cell component is identified to indicate which organelle it represents.

Discovering Animal Cells Self-Study Unit

Discovering Animal Cells Self-Study Unit

The Discovering Animal Cells Set includes slides of the 2 most commonly studied examples of animal cells (human cheek cells and Amphiuma liver).

Cells, Units of Life Slide and Poster Set

Cells, Units of Life Slide and Poster Set

Students easily compare animal and plant cells, single-celled organisms, and specialized cells using this set of 10 slides and helpful poster. They can explore the cell membrane, cytoplasm, and nucleus within a typical animal cell and look at the structure of typical plant cells, identifying the cell wall, chloroplasts, and vacuoles. Students can also observe examples of specialized cells, including blood, skin, and nerve cells. The laminated poster provides full-color, labeled images and descriptive insight into cellular structure.

Cell Study BioKit®

Cell Study BioKit®

Introduces the cell, its basic structure, and general concept. Includes Amoeba, Euglena, onion, elodea tips, cork, microscope slides, coverslips, forceps, razor knives, toothpicks, pipets, Protoslo®, stain, and teacher’s manual with reproducible student guide.

Adding Depth to Instruction with Cell Models

High-quality, detailed models are a tactical way that students can observe and interact with cell structure. Carolina’s wide selection of prokaryotic, eukaryotic, plant, and animal models lets students learn through touch and close observation.

3B® Plant Cell Model

3B® Plant Cell Model

3B® Scientific. Study the structure of a typical plant cell using this greatly enlarged model (magnified 500,000 to 1,000,000x life size). Important organelles are shown in raised relief within the cytoplasm and are depicted in full form and cross section.

3B® Animal Cell Model

3B® Animal Cell Model

3B® Scientific. Use this greatly enlarged, vibrantly colored model to study the structure of a typical animal cell. Significant structures within the cell are shown in raised relief, both in full form and in cross section, but cannot be removed from the cell model. 

Altay Chloroplast Model

Altay Chloroplast Model

Open section shows the inner structures of a typical chloroplast, including the outer and inner membranes, granum, stroma, starch granules, and osmophilic globule.

Somso® Reconstruction of a (Gram-Positive) Bacterial Cell Model

Somso® Reconstruction of a (Gram-Positive) Bacterial Cell Model

This model shows the basal structure, capsule, flagellum, storage granule, lipoprotein layer, cell membrane, mesosome, murein layer, pilus, polyphosphate granule, polysomes, periplasm, thylakoids, vacuole, and DNA.

Explore Teaching Resources

Engage students in hands-on labs with LabSheets, supplement your instruction with handouts and infographics, gain and share scientific insights with Timeless Tips, and streamline your preparation with shopping lists and buying guides.

Explore Teaching Resources

Engage students in hands-on labs with LabSheets, supplement your instruction with handouts and infographics, gain and share scientific insights with Timeless Tips, and streamline your preparation with shopping lists and buying guides.

Skills, Practices, and Data

Investigating cells is an excellent topic for building foundational biology skills such as microscopy and scientific drawing. Our lab skills series equips your students with techniques crucial to their success with free how-to videos, infographics, and classroom posters to support all learning styles. Explore our resources for mastering microscopy, oil immersion, and using laboratory drawings to enhance student learning below.

TOPIC Higher Ed K -12
Micropscopy
Modeling
Measuring
 
Drawing
Analyzing Data
 
Ratios
 
Designing Experiments
 

What’s Next: Membranes, Osmosis, and Diffusion

Once students understand the structure of cells, they begin to understand the important role that cell membranes play in maintaining homeostasis. The structure of the plasma membrane controls how materials move into and out of cells, allowing cells to metabolize and maintain a stable environment. Through exploring osmosis and diffusion, students build on their knowledge of cellular structures by investigating how water, nutrients, gases, and other substances cross membranes and support essential life processes. This connection helps bridge foundational cell biology with more advanced concepts in transport, metabolism, and physiological regulation.

For More Support

Need additional guidance? Our subject matter experts and customer service team are here to help you find the right activities, kits, and resources to support your goals. Reach out to us anytime at product@carolina.com.

Newsletter Signup

Get the latest news, free activities, teacher tips, product info, and more delivered to your inbox.